Expression and Function of Transmembrane-4 Superfamily (Tetraspanin) Proteins in Osteoclasts: Reciprocal Roles of Tspan-5 and NET-6 during Osteoclastogenesis

Background: Osteoclasts are bone-resorbing multinuclear polykaryons essential for bone remodeling, formed through cell fusion of mononuclear macrophage/monocyte lineage precursor cells upon stimulation by the RANK/RANKL system.Recent studies have revealed that a family of tetraspanin proteins, such as CD9, is critically involved in the cell fusion/

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Characteristics of fraud in the agro-industrial complex of Russia

The article discusses measures of state support for the agricultural sector as one of the key Accessories areas of activity of the agro-industrial complex in the Russian Federation, analyzes common fraudulent schemes that act against the interests of state policy in the field of support and development of the fundamental directions of the agro-indu

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Dendrimers for Drug Delivery

Dendrimers have come a long way in the last 25 years since their inception.Originally created as a wonder Hair Mousse molecule of chemistry, dendrimer is now in the fourth class of polymers.Dr.Donald Tomalia first published his seminal work on Poly(amidoamine) (PAMAM) dendrimers in 1985.Application of dendrimers as a drug delivery system started in

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